Series on Discovery of iPS
Cells Fascinating
Part One of Two
By Barb Lyons
Editor's note. This is
reprinted from Wisconsin Right to Life's "Life
Voice Blog" found at
www.wrtl.org/blog.
Kudos to the Milwaukee Journal
Sentinel for its three-part series on how
scientists around the world raced time and each
other to be the first to publish the successful
reprogramming of ordinary human cells to become
pluripotent cells which are like embryonic stem
cells. No embryos were destroyed in the process.
As one who has followed,
written and spoken extensively on stem cells for
the past eight years, I found the series
absolutely fascinating! Even the titles of the
articles are thrilling:
"Rivals race to turn back a
cell's clock"
"Scientists begin digging for
genetic triggers"
"Holy Grail of stem cell
research within reach"
Calling this research the Holy
Grail is mind boggling. And yet, that's what it
could very well be when applied to human
patients sometime in the future. Ethical and
practical research working seamlessly to enhance
treatment for patients with a myriad of
conditions and the possibility of cures -- the
Holy Grail indeed.
The winners in the race to the
finish which occurred in November 2007 were
James Thomson and Junying Yu of UW-Madison and
Shinya Yamanaka and Kazutoshi Takahashi of
Japan. Scientists at other American research
facilities and in other countries were also
racing to be first. As described in the series,
the competition was secretive and fierce as
there is little prestige for coming in second or
third.
The most interesting
revelation is that the task was believed by
virtually everyone to be next to impossible.
Yet, the solution turned out to be so simple
scientists were concerned they had made a fatal
error. Evidence of the simplicity is the
replication of the reprogramming process which
is occurring at rapid speed all over the world.
Why was this discovery so
important when billions are being spent on
embryonic stem cell research? The winners said
it best:
Thomson on destroying the
human embryo to obtain embryonic stem cells: "If
you don't find it at least a little bit creepy,
you haven't thought about it enough."
Yamanaka on viewing embryos
under a microscope: "The difference between my
daughter and these tiny cells looked very small
to me. I can imagine if we transplant this
embryo, it may become just like my daughter, or
I could destroy this and try to make human
embryonic stem cells. " Yamanaka vowed to find
another way.
For a fascinating must-read,
the full series can be found at
www.jsonline.com/search/?keywords=stem+cell+research.
Please send any thoughts you
have to
daveandrusko@gmail.com
Part Two --
Doe v. Gomez: 13 years of state-sponsored
abortion |